Inclusion Criteria:

          -  Participants must have histologically confirmed intracranial meningioma, grade
             II-III,that has recurred or progressed at previous treatment.

          -  Participants must be willing and able to undergo regular MRI scans of the brain.

          -  Participants must have measurable disease, defined as at least one lesion that can be
             accurately measured in at least one dimension as ≥10 mm with MRI, performed within 30
             days prior to study registration.

          -  Patients must have received prior surgical resection and radiation therapy for the
             progressive meningioma.

          -  Patients must have received less than three prior chemotherapy regimens for
             progressive meningioma.

          -  Patients must have available an archival paraffin tumor block sufficient to generate
             at least 20 unstained slides; or, if a paraffin tumor block is unavailable, at least
             20 unstained slides.

          -  Age ≥ 18 years at the time of study enrollment.

          -  ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A) with no deterioration over
             the previous 2 weeks.

          -  Life expectancy of greater than three months

          -  Within 14 days of study registration, participants must have normal organ and marrow
             function as defined below:

               -  leukocytes ≥3,000/mcL

               -  absolute neutrophil count ≥1,500/mcL

               -  hemoglobin ≥90 g/L

               -  platelets ≥100,000/mcL

               -  total bilirubin ≤1.5 x institutional upper limit of normal

               -  AST(SGOT)/ALT(SGPT) ≤2.5 × institutional upper limit of normal

               -  Serum creatinine ≤1.5 x institutional upper limit of normal concurrent with
                  creatinine clearance ≥50 mL/min (measured or calculated by Cockcroft and Gault
                  equation), confirmation of creatinine clearance is only required when creatinine
                  is >1.5xULN

               -  Urine protein ≤1+ on urine dipstick (if 2+ seen on first test, re-test at least
                  24 hours later)

               -  PT/INR/PTT (aPTT) <1.5x institutional upper limit of normal

          -  The effects of AZD2014 on the developing human fetus are unknown. For this reason and
             because mTOR kinase inhibiting agents are known to be teratogenic, female patients
             must be willing to use 2 forms of highly effective contraception (per institution
             standards) from the time of screening until four weeks after discontinuing study, must
             not be breast feeding, and must have a negative pregnancy test prior to start of
             dosing if of child bearing potential or must have evidence of non-childbearing
             potential by fulfilling one of the following criteria at screening: (1)
             post-menopausal women, defined as either women aged more than 50 years and amenorrheic
             for at least 12 months following cessation of all exogenous hormonal treatments, or
             (2) women under 50 years old who have been amenorrheic for at least 12 months
             following the cessation of exogenous hormonal treatments, and have serum
             follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels in the
             postmenopausal range for the institution. Alternatively, women must have documentation
             of irreversible surgical sterilization by hysterectomy, bilateral oophorectomy or
             bilateral salpingectomy but not tubal ligation.

        Male patients should either be surgically sterile or willing to use an effective barrier
        method of contraception during the study and for 16 weeks following the last dose of study
        treatment if sexually active with a female of childbearing potential. If not done
        previously, storage of sperm prior to receiving AZD2014 will be advised to male patients
        with a desire to have children.

          -  Ability to understand and the willingness to sign a written informed consent document
             prior to any study specific procedures, sampling, and analyses.

          -  Ability to swallow and retain oral medication.

        Exclusion Criteria:

          -  Participants with a clinical diagnosis of NF2 (either by NIH or Manchester criteria)
             or with a molecular diagnosis of NF2

          -  Participants who received biopsy only or have received more than 2 prior courses of
             radiation for meningioma

          -  Participants who have had chemotherapy, radiotherapy, biological therapy,
             immunotherapy or other anticancer agents within 14 days (six weeks for nitrosoureas or
             mitomycin C) prior to entering the study.

          -  With the exception of alopecia, any unresolved toxicities from prior anti-tumor
             treatments (excluding corticosteroids) should be no greater than CTCAE (Version 4.0)
             Grade 1 at the time of study entry.

          -  Major surgery within four weeks prior to entry to the study (excluding placement of
             vascular access), or minor surgery (excluding tumor biopsies) within 14 days of first
             dose of study treatment.

          -  Participation in another clinical study with an investigational product during the
             last 21 days.

          -  History of hypersensitivity to active or inactive excipients of AZD2014 or drugs with
             a similar chemical structure or class to AZD2014.

          -  Exposure to strong or moderate inhibitors or inducers of CYP3A4/5, Pgp (MDR1) and BCRP
             if taken within the stated washout periods before the first dose of study treatment
             (see Appendix B)

          -  Exposure to specific substrates of the drug transporters OATP1B1, OATP1B3, MATE1 and
             MATE2K within the appropriate wash-out period (a minimum of 5 x reported elimination
             half-life) before the first dose of study treatment (see Appendix B)

          -  Any hematopoietic growth factors (e.g., filgrastim [granulocyte colony-stimulating
             factor; G-CSF], sargramostim [granulocyte-macrophage colony-stimulating factor;
             GM-CSF]) within 14 days prior to receiving study treatment.

          -  Pre-treatment with other mTOR inhibitors may be allowed and should be discussed with
             the medical monitor.

          -  Current refractory nausea and vomiting, malabsorption syndrome, disease significantly
             affecting gastrointestinal function, resection of the stomach or small bowel,
             symptomatic inflammatory bowel disease or ulcerative colitis, or partial or complete
             bowel obstruction.

          -  Previous meningioma progression during treatment with other mTORC1/2 inhibitors (but
             not mTORC1 inhibitors such as everolimus or other rapalogs).

          -  Uncontrolled intercurrent illness including, but not limited to, ongoing or active
             infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac
             arrhythmia, severe hepatic impairment, interstitial lung disease (bilateral, diffuse,
             parenchymal lung disease), uncontrolled chronic renal diseases (glomerulonephritis,
             nephrotic syndrome, Fanconi Syndrome or renal tubular acidosis), current unstable or
             uncompensated respiratory or cardiac conditions, uncontrolled hypertension, active
             bleeding diatheses, active hepatitis B or C infection, known active human
             immunodeficiency virus (HIV) infection, or psychiatric illness/social situations that
             would limit compliance with study requirements. Screening for chronic conditions is
             not required.

          -  History of other malignancies, except: Malignancy treated with curative intent and
             with no known active disease present for ≥5 years before the first dose of study drug
             and felt to be at low risk for recurrence by treating physician, (2) adequately
             treated non-melanoma skin cancer or lentigo maligna without evidence of disease, (3)
             adequately treated carcinoma in situ without evidence of disease, or (4) Gleason 6
             prostate cancer under observation.

          -  Patients who have experienced any of the following procedures or conditions currently
             or in the preceding 12 months:

               -  coronary artery bypass graft

               -  angioplasty

               -  vascular stent

               -  myocardial infarction

               -  angina pectoris

               -  congestive heart failure New York Heart Association Grade ≥2 (ventricular
                  arrhythmias requiring continuous therapy)

               -  supraventricular arrhythmias including atrial fibrillation, which are
                  uncontrolled

               -  hemorrhagic or thrombotic stroke, including transient ischemic attacks or any
                  other central nervous system bleeding

               -  History of drug abuse or alcohol abuse, as judged by the Investigator

          -  Abnormal echocardiogram (ECHO) or multi-gated acquisition scan (MUGA) at baseline
             (left ventricular ejection fraction [LVEF] <55%). Appropriate correction to be used if
             a MUGA is performed.

          -  Pre-existing renal disease including glomerulonephritis, nephritic syndrome, Fanconi
             Syndrome or renal tubular acidosis.

          -  Mean resting corrected QT interval (QTc), calculated using Fridericia's formula, > 470
             msec obtained from 3 electrocardiograms (ECGs), family or personal history of long or
             short QT syndrome, Brugada syndrome or known history of QTc prolongation or Torsade de
             Pointes within 12 months of the patient entering in the study.

          -  Patients with uncontrolled Type II (HbA1c >8% assessed locally) as judged by the
             investigator or abnormal fasting glucose value defined as >126 mg/dL (>7 mmol/L).

          -  Concomitant medications known to prolong QT interval, or with factors that increase
             the risk of QTc prolongation or risk of arrhythmic events (such as heart failure,
             hypokalemia, congenital long QT syndrome, family history of long QT syndrome or
             unexplained sudden death under 40 years-of-age). See appendix B for a list of
             medications.

          -  Vaccinated with live, attenuated vaccines within four weeks of the first dose of study
             drug.

          -  Judgment by the Investigator that the patient is unsuitable to participate in the
             study and the patient is unlikely to comply with study procedures, restrictions and
             requirements.

          -  Pregnant women are excluded from this study because AZD2014 is an mTORC1/2 inhibiting
             agent with the potential for teratogenic or abortifacient effects. Because there is an
             unknown but potential risk for adverse events in nursing infants secondary to
             treatment of the mother with AZD2014, breastfeeding should be discontinued if the
             mother is treated with AZD2014.

          -  HIV-positive participants on combination antiretroviral therapy are ineligible because
             of the potential for pharmacokinetic interactions with AZD2014. In addition, these
             participants are at increased risk of lethal infections when treated with
             marrow-suppressive therapy. Appropriate studies will be undertaken in participants
             receiving combination antiretroviral therapy when indicated.

          -  Involvement in the planning and/or conduct of the study (applies to both AstraZeneca,
             CRO staff, and/or staff at the CPU).