Inclusion Criteria:

          -  Pathologic diagnosis of non small cell lung cancer, Stage Ⅱ-ⅢA before treatment

          -  EGFR Gene mutated

          -  ECOG 0-1

          -  liver, kidney and bone marrow are functional healthy，WBC>4.0×109/L，PLT>100×109/L
             Hb>10g/dL;Cr<1.8mg/dL，bilirubin<1.5mg/dL，GPT<1.5 upper limit of normal

          -  No vital systems dysfunction or malnutrition

          -  No other malignant diseases in 5 years（except non melanoma or Cervical carcinoma in
             situ）

          -  Have never accepted radiation therapy、overall chemotherapy or biotherapy

          -  Know the whole protocol，Voluntary participate and sign a consent form

        Exclusion Criteria:

          -  Tumor has violated the surrounding tissue organs（T4）

          -  Preoperative have evidence of distant metastasis including the contralateral
             mediastinal lymph nodes

          -  Arrhythmia need anti-arrhythmic treatment（except for β-blockers or
             digoxin），Symptomatic coronary artery disease and myocardial ischemia (myocardial
             infarction) in the past 6 months or more than NYHA class II congestive heart failure

          -  Adverse drug control severe hypertension

          -  Moderate to severe proteinuria

          -  History of HIV infection or activity of chronic hepatitis b or hepatitis c, or other
             active clinical severe infection

          -  Cachexy,organ function decompensation

          -  History of chest radiotherapy

          -  Not fully control the eye inflammation

          -  Epilepsy patients needed treatment（such as Steroids or antiepileptic cure）

          -  Interstitial pneumonia

          -  Drug abuse and medical, psychological or social conditions may interfere with the
             patients involved in the research or have an impact on the results of evaluation

          -  Known or suspected to study drug allergy or to give any drug allergies associated with
             this test

          -  Any unstable situation or may endanger the patient safety and compliance

          -  Fertility and pregnancy or lactation women, and have not been sufficient precautions