1. Female participants, 18 years or older

          2. Measurable disease per radiographic evaluation

          3. Performance status 0 or 1

          4. Available archival tissue sample (within 2 years) or a fresh tumor biopsy may be
             required

          5. Adequate organ, cardiac, and bone marrow function

          6. Dose escalation

               1. Participants with breast cancer:

                    -  Locally advanced or metastatic triple negative breast cancer (ER-negative,
                       PgR-negative, and HER2-negative according to ASCO/CAP guidelines) with
                       disease progression

                    -  No available alternative or curative therapy

                    -  Participants may have received any number of prior therapies for
                       advanced/recurrent and progressive disease

               2. Participants with ovarian cancer:

                    -  Locally advanced or metastatic ovarian cancer with disease progression

                    -  No available alternative or curative therapy Participants may have received
                       any number of prior therapies for advanced/recurrent and progressive disease

          7. Dose expansion

               1. Participants with breast cancer:

                    -  Locally advanced or metastatic triple negative breast cancer (ER-negative,
                       PgR-negative, and HER2-negative according to ASCO/CAP guidelines)

                    -  Disease progression after no more than 3 prior lines of therapy

               2. Participants with ovarian cancer:

                    -  Locally advanced or metastatic ovarian cancer that is platinum-resistant

                    -  Disease progression after no more than 3 prior lines of therapy

        Exclusion:

          1. Received a live, attenuated vaccine within 4 weeks prior to first study treatment

          2. Prior anticancer treatment including approved agents, systemic radiotherapy, or
             investigational therapy within 4 weeks prior first study treatment

          3. Cancer other than the disease under study within 2 years prior to study entry, except
             for some cancers with a low risk of spreading like non-melanoma skin cancers

          4. Inability to swallow oral medications

          5. Participant is breastfeeding, pregnant, or expects to become pregnant during the study

          6. Active autoimmune disease or documented history of autoimmune disease within 2 years
             prior to first study treatment

          7. History of peptic ulcer or stomach bleeding within 6 months prior to first study
             treatment

          8. Use of drugs contraindicated by the protocol within 4 weeks prior to and during study
             treatment

          9. Prior treatment with drugs that suppress the immune system within 2 weeks prior to
             first study treatment

         10. Presence of metastases in the brain or cancer spreading into the cerebrospinal fluid -
             CSF (leptomeningeal disease)

         11. HIV, Hepatitis B, and C test results negative prior to first study treatment

         12. Major surgery within 4 weeks prior to first study treatment

         13. Participants who have previously received maximum cumulative lifetime anthracycline
             dosage or baseline ejection fraction <50% (on heart echography)