Inclusion Criteria:

        Molecular Pre-screening Inclusion criteria (Phase II only)

        1) The patient must sign the molecular pre-screening Inform Consent to allow for the
        molecular pre-screening process. All patients must have documented evidence of EGFR and/or
        cMet aberrations.

        Screening Inclusion Criteria

          1. Able to understand and willing to sign the Informed Consent Form (ICF).

          2. Histologically/cytologically confirmed advanced/metastatic solid tumors with
             measurable disease [Response Evaluation Criteria in Solid Tumors (RECIST) v1.1]:

             Phase I: advanced/metastatic solid tumors including but not limited to NSCLC,
             colorectal cancer, gastric cancer and liver cancer refractory to standard therapy or
             for which no standard therapy is available or accessible.

             Phase II:

             Advanced/metastatic NSCLC Patients have confirmed EGFR mutant and/or cMET aberration,
             and have progressed after standard treatment (including platinum-based therapy) or are
             intolerant to standard treatment. Additionally, patients with T790M mutation have
             received FDA/Health Authority approved therapies (if accessible) for this indication
             (i.e., osimertinib) and have progressed or became intolerant.

             A patient who has refused all currently available therapy is allowed to enroll, but
             must be documented in the source record.

          3. 4) Must have adequate organ function

          4. Regarding prior anti-tumor therapy:

             a. Must have stopped treatment at least 4 weeks or within 5 half-lives Generalized
             radiation therapy must have stopped 3 weeks before first dose of EMB 01, or local
             radiotherapy or radiation therapy for bone metastases must have stopped 2 weeks before
             first dose of EMB-01. No therapeutic radiopharmaceuticals are taken within 8 weeks
             before first dose of EMB-01.

             c. Patients must have recovered to ≤Grade 1 from the adverse effects of such above
             treatment before beginning study treatment.

          5. 6) Female patient with fertility or male patient whose partner has fertility should
             use one or more contraceptive methods for contraception starting from screening period
             and continue throughout the study treatment and for 3 months.

          6. ECOG score 0 or 1 for phase I, and ≤2 for phase II.

        Exclusion Criteria:

        Molecular Pre-screening Exclusion Criteria (Phase II only)

        Subject who meets any of the follow criteria can't be proceeded to clinical screening:

          1. Patients who are unwilling to sign the molecular pre-screening ICF.

          2. Patients for whom local EGFR and/or cMET data or the results of central laboratory
             testing do not meet the molecular pre-screening inclusion criteria.

        Screening Exclusion Criteria

          1. Life expectancy < 3 months.

          2. Subject with primacy central nervous system (CNS) malignancy or symptomatic CNS
             (leptomeningeal or brain) metastases.

          3. Pregnant or nursing females.

          4. Subjects who have had major surgery within 28 days prior to screening.

          5. Serious underlying medical conditions, including but not limited to un-controlled
             hypertension, other cardiovascular disease or diabetes, ongoing or active infection,
             psychiatric, psychological, familial or geographical condition that, in the judgment
             of the investigator, may interfere the compliance with study treatment.