For more information regarding participation in the Trial, please refer to your physician

        Inclusion Criteria:

          -  Women and men ≥18 years of age with Eastern Cooperative Oncology Group (ECOG)
             performance status of 0 or 1

          -  Subject with histologically or cytologically confirmed advanced solid tumor for whom
             no standard treatment is further available.

          -  At least 4 weeks since any previous treatment for cancer

          -  Subject must consent to pretreatment and on treatment tumor biopsies

          -  Adequate organ and marrow function

        Exclusion Criteria:

          -  Patients with primary brain tumors or primary tumors with central nervous system
             metastases as only location of disease. Controlled brain metastases are permitted

          -  Participants with second/other active cancers requiring current treatment

          -  Uncontrolled/significant heart disease

          -  Known History of chronic hepatitis, Positive test for Hepatitis B virus surface
             antigen or Hepatitis C antibody (except participants with liver cancer) or Human
             Immunodeficiency Virus/Acquired Immunodeficiency Syndrome(HIV/AIDS)

          -  Active/uncontrolled autoimmune disease

          -  Active infection

        Other protocol defined inclusion/exclusion criteria could apply