Inclusion Criteria

          1. Capable of giving signed informed consent which includes compliance with the
             requirements and restrictions listed in the informed consent form (ICF) and in this
             protocol.

          2. Chinese subjects at least 18 years of age at the time of study entry.

          3. Eastern Cooperative Oncology Group (ECOG) performance status of ≤2

          4. Adequate hematological and organ function.

          5. Presence of radiographically measurable lymphadenopathy or extranodal lymphoid
             malignancy.

          6. Pathologically confirmed MCL, with documentation of chromosome translocation t(11;14)
             (q13;q32) and/or overexpression of cyclin D1 in association with other relevant
             markers (eg, CD5, CD19, CD20, PAX5). Disease had relapsed after or been refractory to
             previous treatment.

          7. Diagnosis of CLL that meets published diagnostic criteria. Must have received ≥ 1
             prior systemic therapies for CLL.

          8. Active disease per iwCLL 2018 criteria that requires treatment. (CLL only)

          9. Other relapsed/refractory B-cell malignancies without stand of care (phase 1 only).

        Exclusion criteria

          1. Prior malignancy, except for adequately treated basal cell or squamous cell skin
             cancer, in situ cervical cancer, or other cancer from which the subject had been
             disease free for ≥2 years or which would not have limited survival to <2 years.

          2. Significant cardiovascular disease.

          3. Known central nervous system involvement of lymphoma/leukemia or leptomeningeal
             disease.

          4. Known history of HIV, serologic status reflecting active hepatitis B or C infection.

          5. Major surgery within 4 weeks before first dose of study drugs.

          6. Uncontrolled autoimmune hemolytic anemia or idiopathic thrombocytopenia purpura.

          7. Required or received anticoagulation with warfarin or equivalent vitamin K antagonist
             (eg, phenprocoumon).

          8. Prior exposure to a BCR or BCL-2 inhibitor.

          9. Use of a strong inhibitor or inducer of CYP3A.

         10. Breastfeeding or pregnant.