Inclusion Criteria:

          -  The subject must understand the requirements of the study and voluntarily sign the
             informed consent form (ICF)

          -  All subjects must have a histologically confirmed unresectable TCC (including renal
             pelvis, ureters, urinary bladder, and urethra)

          -  Failed one and only one line of cisplatin-based chemotherapy per FDA guidelines.

          -  Subjects must have an area of tumor amenable to excisional biopsy for the generation
             of TIL separate from, and in addition to , a target lesion to be used for response
             assessment.Have at least one resectable lesion to generate TILs

          -  At least one measurable target lesion as defined by RECIST version 1.1

          -  An Eastern Cooperative Oncology Group (ECOG) performance status of =< 1

          -  Estimated life expectancy of >= 6 months

          -  Adequate bone marrow function

          -  Adequate organ function

          -  Subjects must be seronegative for the human immunodeficiency virus (HIV)

          -  Recovered from all prior anticancer therapy-related AEs to grade 1 or less

          -  Negative serum pregnancy test (female subjects of childbearing potential)

          -  Subjects of childbearing potential must be willing to practice an approved method of
             birth control starting at the time of informed consent and for 12 months after the
             completion of the study treatment regimen

          -  Must be able and willing to comply with the study visit schedule and protocol
             requirements including long-term follow-up

        Exclusion Criteria:

          -  Have had another primary malignancy within the previous 3 years (with the exception of
             carcinoma in situ of the breast, cervix, or localized prostate cancer and non-melanoma
             skin cancer that has been adequately treated)

          -  Have received prior cell transfer therapy that included a nonmyeloablative or
             myeloablative chemotherapy regimen

          -  Prior treatment with anti-PD-1, or anti-PD-L1 therapeutic antibody, or
             pathway-targeting agents

          -  Chemotherapy or radiotherapy with projected completion within 4 weeks of initiating
             study treatment

          -  Bisphosphonate therapy for symptomatic hypercalcemia

          -  Have had treatment with systemic immunostimulatory agents (including, but not limited
             to, interferon [IFN]-alpha or interleukin [IL]-2) within 6 weeks before initiation of
             study treatment

          -  Active or prior documented autoimmune or inflammatory disorders

          -  Subjects who have any form of human immondeficiency virus (HIV)infection

          -  Have severe infections within 4 weeks before initiation of study treatment

          -  Have received a live or attenuated vaccine within 28 days of the non-myeloablative
             lymphodepletion (NMA-LD regimen)

          -  Subjects with a history of hypersensitivity reaction(s) to any component of the LN-145
             therapy and/or the other study drugs

               -  Mean QT interval corrected for heart rate using Fridericia's formula (QTcF) >=
                  450 msec for males (and >= 470 msec for females) calculated from 3
                  electrocardiograms (ECGs) (within a 30-minute timeframe) or history of familiar
                  long-QT syndrome

          -  Subjects who have a left ventricular ejection fraction (LVEF) < 45% or who are New
             York Heart Association functional classification class II or higher

          -  Serious illnesses or medical conditions, which would pose increased risk for study
             participation and/or compliance with the protocol

          -  Known clinically significant liver disease

          -  Have obstructive or restrictive pulmonary disease and have a documented FEV1 (forced
             expiratory volume in 1 second) of =< 60%

          -  Subjects with known primary central nervous system (CNS) malignancy or symptomatic CNS
             metastases

          -  Subjects who are pregnant or breastfeeding

          -  Active infection including tuberculosis (TB), hepatitis B, hepatitis C, or human
             immunodeficiency virus

          -  Treatment with any other investigational agent within 4 weeks before initiation of
             study treatment