Inclusion Criteria:

          -  Diagnostic criteria of AML, without having achieved remission after at least 2
             attempts at induction chemotherapy, no attempt of induction if relapsed within 6
             months of induction or no attempt of induction if relapsed after 6 months post
             induction therapy.

          -  Age 18 to 55 years of age.

          -  Planned or scheduled to receive an allogeneic hematopoietic stem cell transplant
             (HSCT) using peripheral blood (PB) or bone marrow (BM) stem cells. Cord blood donor
             cells are not allowed.

          -  Planned or scheduled to receive a standard conditioning regimen consisting of
             Busulfan, Fludarabine, and TBI.

          -  Performance status: Karnofsky ≥ 70% within 28 days of study registration

          -  LVEF ≥ 50% by MUGA or echocardiogram within 28 days of study registration.

          -  FEV1 and FVC ≥ 50% predicted, DLCO (corrected for hemoglobin) ≥ 50% of predicted
             within 28 days of study registration.

          -  Creatinine clearance 60 mL/min/1.73 m^2 within 28 days of study registration

          -  Serum bilirubin less than or equal to 1.5 times upper limit of normal (ULN);

          -  AST/ALT less than or equal to 2.5 times ULN;

          -  Alkaline phosphatase less than or equal to 2.5 times ULN

        Exclusion Criteria:

          -  Known history of non-compliance with medication, scheduled clinic visits, or
             self-care.

          -  In the opinion of the investigator, no appropriate caregivers identified.

          -  HIV1 (Human Immunodeficiency Virus-1) or HIV2 positive

          -  Active infection including Hepatitis B and Hepatitis C.

          -  In the opinion of the physician investigator, uncontrolled medical or psychiatric
             disorders.

          -  In the opinion of the physician investigator, uncontrolled infections, defined as
             positive blood cultures within 72 hours of study entry or evidence of progressive
             infection by imaging studies such as chest CT scan within 14 days of registration.

          -  Active central nervous system (CNS) leukemia.

          -  Prior allogeneic HSCT.

          -  Pregnant or breastfeeding. Women of child bearing potential (WCBP) are required to
             have a negative serum or urine pregnancy test within 7 days of initiation of
             conditioning regimen.