Inclusion Criteria:

          -  Patients must have documented CEA-expressing pancreatic adenocarcinoma with
             unresectable liver metastases. Documentation of CEA-expressing adenocarcinoma may be
             demonstrated by an elevated serum CEA level (≥ 10 ng/mL) or by the detection of CEA on
             the cell surface of adenocarcino3.

          -  Documentation of disease progression of pancreatic adenocarcinoma following the
             initiation of first-line treatment with FOLFIRINOX or gemcitabine-based therapy.ma
             cells by immunohistochemistry (IHC).

          -  The primary pancreatic tumor may be intact and limited lung metastases (≤ 3 lesions,
             none > 1 cm in longest diameter) and lymphoid metastases (≤ 3 lesions, none > 1 cm in
             longest diameter) are permitted.

          -  There must be at least one measurable metastatic liver lesion ( ≥ 10 mm in longest
             diameter).

          -  ECOG performance status of 0 or 1.

          -  Be willing and able to comply with the study schedule and all other protocol
             requirements.

          -  Females of childbearing potential must have 2 negative pregnancy tests prior to the
             start of study treatment, and must agree to pregnancy tests during the study; sexually
             active female and male patients must be willing to use an effective birth control to
             avoid pregnancy.

        Exclusion Criteria:

          -  Received anti-cancer chemotherapy or investigational systemic anti-cancer treatments
             other than first line FOLFIRINOX or gemcitabine-based chemotherapy for advanced
             pancreatic adenocarcinoma.

          -  Received FOLFIRINOX or gemcitabine-based therapy within 14 days before receiving the
             first dose of study treatment.

          -  Have any unresolved toxicity > Grade 1 from previous anticancer therapy, except for
             stable chronic toxicities (≤ Grade 2) that are not expected to resolve.

          -  Have a history of histologically confirmed metastases outside the liver, lungs, or
             lymph nodes.

          -  More than 50% replacement of one or both hepatic lobes with tumor.

          -  Tumor causing biliary obstruction not amenable to stenting.

          -  Received prior anti-CEA agents, CAR-T, CAR-T cell line, CAR-NK, CAR-pNK, or CAR-NK
             cell line therapies.

          -  Have any clinically significant low baseline lab results for hemoglobin, platelet
             counts, or neutrophil counts at screening.

          -  Has any untreated or ongoing intra-abdominal infection or bowel obstruction.

          -  Has any clinically significant elevated baseline lab results for serum creatinine,
             aspartate aminotransferase (AST), and total bilirubin (except for patients in whom
             hyperbilirubinemia is attributed to Gilbert's syndrome), and alkaline phosphatase at
             screening.

          -  Known HIV or acquired immunodeficiency syndrome-related illness, acute or history of
             chronic hepatitis B or C.

          -  Female patients who are pregnant or breastfeeding.

          -  Has active bacterial, viral or fungal infections.

          -  Has any significant medical condition, laboratory abnormality, or psychiatric illness
             that would prevent the patient from participating in the study.

          -  Has any condition, including the presence of laboratory abnormalities that places the
             patient at an unacceptable risk if the patient was to participate in the study.

          -  Are receiving medications that are strong inducers CYP3A4 or CYP2C8 within 2 weeks of
             initiating treatment in the Bridging Therapy Period (rifampicin, carbamazepine,
             phenytoin, efavirenz, nevirapine, rifabutin, rifapentine, St. John's wort).

          -  Are receiving medications that inhibit CYP3A4 or CYP2C8 within 1 week of initiating
             treatment in the Bridging Therapy Period (ketoconazole and other imidazole
             antifungals, erythromycin, clarithromycin, itraconazole, voriconazole, fluoxetine,
             gemfibrozil, cimetidine, lopinavir, nefazodone, telaprevir, ritonavir, saquinavir,
             indinavir, or nelfinavir).

          -  Are receiving medications that inhibit UGT1A1 within 1 week of initiating
             nanoliposomal irinotecan therapy (atazanavir, gemfibrozil, indinavir).

          -  Left ventricular ejection fraction (LVEF) < 40%