Inclusion Criteria:

          1. Voluntary participation in the clinical study; fully understands and is informed of
             the study and has signed the Informed Consent Form (ICF); willing to comply with and
             able to complete all trial procedures.

          2. The gender is not limited. When ICF is signed, the age is ≥ 18 years and ≤ 70 years
             old.

          3. Histologically confirmed untreated gastric cancers, mainly adenocarcinoma.

          4. Within 4 weeks prior to first dose, determined by the Independent Radiology Review
             Committee (IRRC) as: ≥ T3 and number of lymph node metastases ≥ 1 and no distant
             metastasis.

          5. Prior to enrollment, the attending physician will evaluate to determine the
             eligibility for a R0 resection for the purpose of radical treatment.

          6. Have good cardiac function and can be treated with radical resection.

          7. tumor specimen testing results are PD-L1 positive (CPS ≥10). Subjects must provide the
             tumor tissues at screening or in the investigated surgery (if any), for PD-L1
             expression level assessment.

          8. Within 7 days before the first use of the study drug, ECOG: 0 ~ 1;

          9. Expected survival 12 weeks;

         10. The functions of the vital organs meet requirements.

        Exclusion Criteria:

          1. Existence of other active malignant tumors within 5 years or at the same time.

          2. Plan to perform or have undergone an organ or bone marrow transplant.

          3. Myocardial infarction and poorly controlled arrhythmias occurred within 6 months prior
             to the first dose.

          4. Existence of grade III - IV cardiac disorders defined by the NYHA or echocardiogram
             shows: LVEF (left ventricular ejection fraction) < 50%.

          5. Human immunodeficiency virus (HIV) infection.

          6. Patients with active tuberculosis.

          7. Patient with previous or current interstitial pneumonia, pneumoconiosis, radiation
             pneumonitis, drug-associated pneumonia, severely impaired lung function, etc.

          8. Patients who have previously received other antibody/drug treatments for immune
             checkpoints, such as PD-1, PD-L1, and CTLA4 treatments.

          9. Have diseases that may increase the risk of participating in the study and using the
             study medications, or other severe, acute, and chronic diseases and therefore are
             judged by the investigator to be unsuitable for clinical studies.