Inclusion Criteria:

          -  Must have disease progression after treatment with available therapies that are known
             to confer clinical benefit or must be intolerant to or ineligible for standard
             treatment.

          -  Histologically confirmed advanced solid tumors (protocol-defined select solid tumors)
             with measurable lesions per Response Evaluation Criteria In Solid Tumors Version 1.1
             (RECIST v1.1) that are considered nonamenable to surgery or other curative treatments
             or procedures.

          -  ECOG performance status score of 0 or 1.

          -  Life expectancy > 12 weeks.

          -  Willingness to avoid pregnancy or fathering children.

        Exclusion Criteria:

        Exclusion Criteria:

          -  Laboratory values outside the Protocol-defined ranges.

          -  Clinically significant cardiac disease.

          -  History or presence of an ECG that, in the investigator's opinion, is clinically
             meaningful.

          -  Untreated brain or central nervous system (CNS) metastases or brain or CNS metastases
             that have progressed (eg, evidence of new or enlarging brain metastasis or new
             neurological symptoms attributable to brain or CNS metastases).

          -  Known additional malignancy that is progressing or requires active treatment.

          -  Has not recovered to ≤ Grade 1 or baseline from toxic effects of prior therapy
             (including prior IO) and/or complications from prior surgical intervention before
             starting study treatment.

          -  Prior receipt of an anti-PD-L1 therapy.

          -  Treatment with anticancer medications or investigational drugs within protocol-defined
             intervals before the first administration of study drug.

          -  A 28-day washout for systemic antibiotics is required.

          -  Probiotic usage while on study and during screening is prohibited.

          -  Active infection requiring systemic therapy.

          -  Known history of HIV

          -  Evidence of hepatitis B virus or hepatitis C virus infection or risk of reactivation.