Inclusion Criteria:

        Criteria for Inclusion:

          1. Age ≥ 18 years at the time of signing the informed consent form.

          2. Histologically confirmed advanced, recurrent or metastatic injectable solid tumor and
             has received the following prior therapy:

               1. HNSCC: Subject must have been previously treated with a platinum-based
                  chemotherapy regimen and/or a programmed cell death-protein 1 (PD-1) inhibitor.

               2. TNBC: Subject must have been treated with at least 1 chemotherapy regimen and/or
                  PD-L1 or PD-1 inhibitor for metastatic disease.

               3. ATC: Subject must be considered inoperable and not considered to benefit from
                  additional chemotherapy and/or radiation.

               4. cSCC: Subject must have previously been treated with radiation therapy and/or
                  chemotherapy and/or PD-L1 or PD-1 inhibitor.

               5. Subjects with other advanced solid tumors that have progressed following standard
                  therapy or for which there is no standard of care therapy with an overall
                  survival (OS) benefit.

          3. Measurable disease per RECIST v1.1 and ≥1 lesion that is measurable (ie, ≥1.0 cm by
             CT, MRI, or ruler or caliper measurements for cutaneous lesions or other superficial
             lesions in longest diameter [non-lymph nodes] or ≥1.5 cm in shortest diameter for
             lymph nodes) and amenable to tumoral injection and biopsy per Investigator assessment.

          4. Agrees to have a pre-treatment tumor biopsy within 7 days prior to the first dose of
             CDK-002, and 2 on-treatment tumor biopsies of the same lesion. Biopsies may be core
             needle, incisional, or excisional biopsies. For cutaneous lesions, a punch biopsy may
             be acceptable. Fine needle aspiration (FNA) is not acceptable.

          5. Understands and can comply with the study requirements and has signed the informed
             consent form.

          6. Eastern Cooperative Oncology Group (ECOG) Performance Status score of 0 or 1.

          7. Life expectancy of at least 3 months.

          8. Acceptable liver function.

          9. Acceptable renal function.

         10. Acceptable hematologic status.

         11. Negative serum pregnancy test (for women of child-bearing potential) within 72 hours
             before the first dose of CDK-002.

        Exclusion Criteria:

        Criteria for Exclusion:

          1. Prior treatment with a STING agonist.

          2. Cytotoxic chemotherapy, biologic agents, investigational agents, or radiation therapy
             within 4 weeks prior to the first dose of CDK 002 (6 weeks for nitrosoureas or
             mitomycin C). The interval can be reduced to 2 weeks for bone-only radiation therapy.

          3. Small-molecule kinase inhibitors or hormonal anticancer agents within 14 days prior to
             the first dose of CDK 002.

          4. Clinically significant ongoing AEs that have not returned to baseline or to Grade 1
             NCI CTCAE v5.0.

          5. Immunosuppressive agents including corticosteroids within 14 days of first dose of CDK
             002. Topical, intranasal or inhaled corticosteroids, physiologic doses of systemic
             steroids or limited treatment with systemic steroids (ie, for IV contrast prophylaxis)
             may be administered with Sponsor approval.

          6. Major surgery within 6 weeks or minor surgery (excluding tumor biopsies) within 14
             days prior to the first dose of CDK 002 or if subject has not clinically recovered.

          7. Clinically active central nervous system (CNS) metastases or carcinomatous meningitis.
             Subjects with stable brain metastasis may be enrolled with Sponsor approval.

          8. Metastatic liver involvement that exceeds one-third of total liver volume.

          9. Clinically significant cardiovascular disease including but not limited to New York
             Heart Association Class III or IV heart failure, myocardial infarction or stroke
             within the past 6 months prior to the first dose of CDK 002, uncontrolled arrhythmia,
             or severe aortic stenosis. Sponsor approval of subjects with an arrhythmia is
             required.

         10. History of myocarditis.

         11. Active, uncontrolled bacterial, viral, or fungal infections requiring systemic
             therapy. Prophylactic antibiotics are acceptable.

         12. Prior organ or stem cell transplant.

         13. Primary immune deficiency.

         14. Pregnant or nursing women.

         15. Active Hepatitis B or C infection.