Inclusion Criteria:

          -  Advanced IDH mutant hematologic malignancy

          -  Patients must have received prior therapy

          -  Blasts at least 5% in bone marrow.

          -  Patients must have a qualifying IDH1 R132, IDH2 R140 or IDH2 R172 mutation

          -  Eastern Cooperative Oncology Group (ECOG) 0-2

          -  Adequate organ function

          -  Ability to swallow capsules or tablets

          -  Ability to comply with outpatient treatment, laboratory monitoring, and required
             clinic visits for the duration of study participation

          -  Willingness of men and women of reproductive potential to observe conventional and
             effective birth control for the duration of treatment and for 3 months following the
             last dose of study treatment.

        Exclusion Criteria:

          -  Investigational agent or anticancer therapy within 2 weeks or 5 half-lives, whichever
             is shorter; or investigational monoclonal antibody within 4 weeks prior to planned
             start of LY3410738

          -  Major surgery within 4 weeks prior to planned start of LY3410738.

          -  Active, uncontrolled clinically significant systemic bacterial, viral, fungal or
             parasitic infection or an unexplained fever > 38.5ºC during screening or on the first
             day of study drug administration.

          -  Another concurrent malignancy requiring active therapy.

          -  Active central nervous system involvement

          -  Any unresolved toxicities from prior therapy greater than CTCAE v5.0 Grade 2 at the
             time of starting study treatment except for alopecia.

          -  History of hematopoietic stem cell transplant (HSCT) or CAR-T therapy within 60 days
             of the first dose of LY3410738

          -  Clinically significant cardiovascular disease

          -  Active hepatitis B virus (HBV)

          -  Active hepatitis C virus (HCV)

          -  Clinically significant active malabsorption syndrome or other condition likely to
             affect gastrointestinal (GI) absorption of the study drug

          -  Current treatment with certain strong cytochrome P450 3A4 (CYP3A4) inhibitors or
             inducers and/or P-gp inhibitor, with the exception of patients being treated with
             allowed antifungal inhibitors of CYP3A4

          -  Treatment with proton pump inhibitor (PPIs) within 7 days of starting LY3410738

          -  Any serious underlying medical or psychiatric condition (e.g. alcohol or drug abuse),
             dementia or altered mental status or any issue that would impair the ability of the
             patient to understand informed consent or that in the opinion of the investigator
             would contraindicate the patient's participation in the study or confound the results
             of the study

          -  Known human immunodeficiency virus (HIV), excluded due to potential drug-drug
             interactions between anti-retroviral medications and LY3410738

          -  Pregnancy, lactation or plan to breastfeeding during the study or within 90 days of
             the last dose of study intervention

          -  Known hypersensitivity to any of the components of LY3410738 or its formulation