Inclusion Criteria:

          1. Histologically or cytologically confirmed pancreatic adenocarcinoma or adeno-squamous
             carcinoma with liver metastasis.

               1. Subjects with additional sites of metastasis, except known brain metastasis, are
                  eligible.

               2. Histologies excluded include squamous, small cell carcinoma, and acinar cell
                  carcinoma. However, adeno-squamous histology can be enrolled.

               3. Patients who have recurrence or metastasis after surgery and adjuvant therapy do
                  not need repeat biopsy for confirmation of recurrence if clinical suspicion is
                  high per scans (MRI/CT scan), with and without CA 19-9 elevation, specifically if
                  biopsy is unsafe or technically difficult.

          2. Patients with no prior lines of therapy for the treatment of stage IV metastatic
             disease.

               1. Patients could have had prior neoadjuvant or adjuvant chemotherapy or
                  chemo-radiotherapy.

             i. Patients who received gemcitabine-based adjuvant chemotherapy can enroll if they
             progress greater than 6 months after completion of the therapy; ii. Patients who
             progress while on adjuvant FOLFIRINOX can enroll immediately.

          3. Male and female patients at least 18 years of age

          4. Laboratory data as specified below:

             Hematology:

             - ANC greater than 1500 cells/mm3,

             - platelet count greater than 100,000 cells/mm3, and

             - Hemoglobin greater than 8 g/dL.

               -  Hepatic

                    -  Total bilirubin less than 1.5 X ULN;

                    -  alanine aminotransferase (ALT) or aspartate aminotransferase (AST) less than
                       3 X ULN.

             For patients with known liver metastases or liver neoplasms: alanine aminotransferase
             (ALT) or aspartate aminotransferase (AST) less than 6.0 X ULN and total bilirubin less
             than 3 x ULN.

               -  Renal:

                    -  serum creatinine WNL or creatinine clearance greater than 50 mL/min.

          5. QT intervals: QTc less than or equal to 470 msec for men and less than or equal to 490
             msec for women. (As measured by Hodges' Equation: QTc = QT + 1.75(rate-60) where QTc =
             corrected QT interval and rate = ventricular rate/min).

          6. Estimated life expectancy of at least 3 months

          7. ECOG Performance Status 0-1.

          8. Ability to operate the Novo TTF-100L (P) system.

          9. Patients must have measurable disease on scans per RECIST 1.1.

         10. Negative serum pregnancy test within 14 days prior to the first dose of study therapy
             for women of child-bearing potential (WCBP), defined as a sexually mature woman who
             has not undergone a hysterectomy or who has not been naturally post-menopausal for at
             least 24 consecutive months (i.e., who has had menses any time in the preceding 24
             consecutive months). Sexually active WCBP and male subjects must agree to use adequate
             methods to avoid pregnancy (oral, injectable, or implantable hormonal contraceptive;
             tubal ligation; intra-uterine device; barrier contraceptive with spermicide; or
             vasectomized partner) throughout the study and for 28 days after the completion of
             study treatment.

        Exclusion Criteria:

        1. Previous front-line therapy for metastatic disease.

          1. Patients with known brain metastasis.

          2. Cardiac conduction abnormalities such as 2nd and 3rd heart-block requiring a
             pacemaker.

          3. Patient with cardiac or abdominal pacemakers or stimulators.

          4. Significant risk of cardiac drug toxicity due to congestive heart failure or history
             of myocardial infarction.

          5. Any other condition including but not limited to major co-morbidities, which in the
             opinion of the investigator would render the patient ineligible.

          6. Concomitant use of drugs that have black box warning of Torsades de Pointes will also
             be prohibited if cannot be replaced by another drug.

          7. Known sensitivity to conductive hydrogels.

        10. Patients who are pregnant or breastfeeding.