Inclusion Criteria:

          1. Age: 18 years old or older, male or female.

          2. Patients must have histologically or cytologically confirmed tumors of the following
             types.

          3. Dose Escalation Phase: Patients with PMF, PV/ET-MF

               1. Intermediate or high-risk primary myelofibrosis, post-polycythemia vera
                  myelofibrosis, or post-essential thrombocythaemia myelofibrosis which failed
                  standard treatment.

               2. Symptomatic splenomegaly

               3. Not undergone splenectomy or splenic radiation therapy within 6 months prior to
                  screening.

          4. Dose expansion phase: Patients with PMF, PV/ET-MF who relapsed or are intolerant to
             standard treatment, and relapsed/refractory AML

          5. Platelet count ≥ 100 × 10e9/L within 14 days before study drug administration

          6. Absolute neutrophil count (ANC) ≥ 1.5 × 10e9/L within 14 days before study drug
             administration

          7. Women of childbearing potential negative pregnancy test at screening. Female patients
             of childbearing potential, or male patients and their partners should agree to
             effective contraception from signing ICF until 6 months after the last dose of study
             drug.

        Exclusion Criteria:

        Patients who meet any of the following exclusion criteria will be excluded from the
        clinical study:

          1. Allergic to any component of LNK01002.

          2. Serum total bilirubin greater than 1.5 times the upper limit of the normal (ULN)
             reference range, except patients diagnosed as Gilbert's disease

          3. ALT or AST higher than 3 times the ULN reference range without hepatic involvement by
             leukemia, which are excluded if higher than 5 times the ULN

          4. Glomerular filtration rate or estimated creatinine clearance < 50 mL/min according to
             the Cockcroft-Gault formula;

          5. Serum amylase or lipase levels higher than the ULN and considered clinically
             significant

          6. International normalized ratio (INR) or partial activated prothrombin time (aPTT)
             above 1.5 times the ULN reference range

          7. Known history of clinically significant liver disease, including viral or other
             hepatitis:

             a) Patients with hepatitis B or hepatitis C may be enrolled if they have a negative
             polymerase chain reaction (PCR)

          8. Known human immunodeficiency virus (HIV) infection;

          9. Clinically significant cardiovascular diseases, including acute myocardial infarction,
             unstable angina, coronary artery bypass surgery within 6 months before enrollment,
             congestive heart failure with New York Heart Association (NYHA) classification of III
             or above, left ventricular ejection fraction (LVEF) < 50%, or uncontrolled
             hypertension, cardiac arrhythmia;

         10. Patients with history or presence of clinically relevant non-malignant CNS disease
             requiring treatment

         11. Patients who have received systemic antineoplastic therapy or radiotherapy within 2
             weeks prior to start of study treatment:

         12. Patients who have received hematopoietic stem cell transplantation (HSCT) within 60
             days prior to the start of study treatment, or are receiving immunosuppressive therapy
             after HSCT at screening, or have graft-versus-host disease (GVHD) requiring drug
             control:

         13. Received anti-tumor Chinese herbal medicine treatment within 1 week before the start
             of study treatment;

         14. Received CYP3A substrates, CYP2B6 substrates, CYP2C substrates, OATP1B3 substrates,
             UGT1A1 inhibitors, or UGT1A3 inhibitors less than one week or 5 half-lives (whichever
             is longer) prior to the start of study treatment;

         15. Uncontrolled, active infections requiring intravenous antibiotic treatment;