Overview

NCI Definition: An acute leukemia of ambiguous lineage in which there is a dual population of blasts with each population expressing markers of a distinct lineage (myeloid and lymphoid or B-and T-lymphocyte). (WHO, 2001) -- 2003 [1]

Significant Genes in Acute Bilineal Leukemia

ABL1 +

ASXL1 +

BCR +

DEK +

FLT3 +

IDH2 +

KMT2A +

MECOM +

NUP214 +

RPN1 +

RUNX1 +

TP53 +

Disease Details

Parent(s)
Mixed Phenotype Acute Leukemia

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.