Overview

NCI Definition: A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma. [1]

Significant Genes in Adenocarcinoma

KRAS +

UGT1A1 +

Disease Details

Synonyms
Poorly Differentiated Adenocarcinoma, Metastatic adenocarcinoma, Adenocarcinoma, NOS, Invasive Adenocarcinoma, ADENOCARCINOMA, MALIGNANT, Invasive Poorly Differentiated Adenocarcinoma
Parent(s)
Carcinoma
Children
Combined Hepatocellular Carcinoma and Cholangiocarcinoma, Mucinous Adenocarcinoma, Sweat Gland Carcinoma, Anal Adenocarcinoma, Parathyroid Gland Carcinoma, Serous Adenocarcinoma, Primary Peritoneal Adenocarcinoma, Thyroid Gland Adenocarcinoma, Ureter Adenocarcinoma, Cervical Adenocarcinoma, Esophageal Adenocarcinoma, Breast Adenocarcinoma, Appendix Adenocarcinoma, Endometrioid Adenocarcinoma, Sebaceous Carcinoma, Lung Adenocarcinoma, Cystadenocarcinoma, Ovarian Adenocarcinoma, Ampulla of Vater Adenocarcinoma, Papillary Adenocarcinoma, Prostate Adenocarcinoma, Mesonephric Adenocarcinoma, Intestinal Type Adenocarcinoma, Scirrhous Adenocarcinoma, Colorectal Adenocarcinoma, Adrenal Cortex Carcinoma, Bile Duct Adenocarcinoma, Bladder Adenocarcinoma, Endometrial Adenocarcinoma, Salivary Gland Adenocarcinoma, Cecum Adenocarcinoma, Gastric Adenocarcinoma, Villous Adenocarcinoma, Vulvar/Vaginal Adenocarcinoma, Seminal Vesicle Adenocarcinoma, Adenocarcinoma of the Gastroesophageal Junction, Sinonasal Adenocarcinoma, Gallbladder Adenocarcinoma, Pituitary Gland Carcinoma, Basophilic Adenocarcinoma, Renal Cell Carcinoma, Small Intestinal Adenocarcinoma, Signet Ring Cell Carcinoma, Fallopian Tube Adenocarcinoma, Renal Pelvis Adenocarcinoma, Clear Cell Adenocarcinoma, Tubular Adenocarcinoma, Adenocarcinoma of Unknown Primary, Paget Disease, and Hepatocellular Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.