Diseases /

Adrenal Cortex Carcinoma

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Associated Genetic Biomarkers

Overview

NCI Definition: A rare, usually large (greater than 5cm), malignant epithelial tumor arising from the adrenal cortical cells. Symptoms are usually related to the excessive production of hormones, and include Cushing's syndrome and virilism in women. Common sites of metastasis include liver, lung, bone, and retroperitoneal lymph nodes. Advanced radiologic procedures have enabled the detection of small tumors, resulting in the improvement of the 5-year survival. [1]

Clinical Trials

View Clinical Trials for Adrenal Cortex Carcinoma

Significant Genes in Adrenal Cortex Carcinoma

AXL +

MET +

RET +

Disease Details

Synonyms
cancer of the adrenal cortex, Carcinoma of Adrenal Cortex, Adrenal Cortical Adenocarcinoma, Cortical Cell Carcinoma, Adrenal Cortex Cancer, CARCINOMA, ADRENOCORTICAL, MALIGNANT, Adrenocortical Carcinoma, Adrenal Cortical Carcinoma, adrenocortical cancer, Adenocarcinoma, Adrenocortical, Malignant, Adrenal Cortex Adenocarcinoma, Adrenocortical carcinoma, NOS, Carcinoma of the Adrenal Cortex
Parent(s)
Malignant Adrenal Cortex Neoplasm
OncoTree Name
Adrenocortical Carcinoma
OncoTree Code
ACC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.