Overview

NCI Definition: A benign or malignant (primary or metastatic) neoplasm affecting the adrenal glands. [1]

Adrenal gland neoplasms most frequently harbor alterations in TP53, CTNNB1, CDKN2A, ATRX, and RB1 [2].

Most Commonly Altered Genes in Adrenal Gland Neoplasm

TP53 Mutation, CTNNB1 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, and ATRX Mutation are the most common alterations in adrenal gland neoplasm [2].

Top Alterations in Adrenal Gland Neoplasm

Disease Details

Synonyms
Neoplasm of the Adrenal Gland, Adrenal Neoplasm, Tumor of Adrenal Gland, Adrenal Gland Tumor, Tumor of the Adrenal Gland, Neoplasm of Adrenal Gland, Adrenal Neoplasms, Adrenal Tumor
Parent(s)
Endocrine Neoplasm
Children
Adrenal Cortex Neoplasm and Adrenal Gland Cancer
OncoTree Name
Adrenal Gland
OncoTree Code
ADRENAL_GLAND

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.