Diseases /
Aggressive Non-Hodgkin Lymphoma
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Associated Genetic Biomarkers
Overview
NCI Definition: A non-Hodgkin lymphoma with an aggressive clinical course. Representative examples include Burkitt lymphoma, mantle cell lymphoma, and angioimmunoblastic T-cell lymphoma. [1]
Clinical Trials
Significant Genes in Aggressive Non-Hodgkin Lymphoma
Disease Details
Parent(s)
Non-Hodgkin Lymphoma by Clinical Course
Children
Grade 3 Follicular Lymphoma, T-Cell Lymphoblastic Lymphoma, Adult T-Cell Leukemia/Lymphoma, Peripheral T-Cell Lymphoma, Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma, B-Cell Lymphoblastic Lymphoma, Primary Cutaneous Gamma-Delta T-Cell Lymphoma, Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma, Hepatosplenic T-Cell Lymphoma, Peripheral T-Cell Lymphoma, Not Otherwise Specified, Nasal Type Extranodal NK/T-Cell Lymphoma, Angioimmunoblastic T-Cell Lymphoma, Anaplastic Large Cell Lymphoma, ALK-Negative, Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type, Mantle Cell Lymphoma, Sezary Syndrome, Enteropathy-Associated T-Cell Lymphoma, Burkitt-Like Lymphoma with 11q Aberration, Diffuse Large B-Cell Lymphoma Activated B-Cell Type, and Burkitt Lymphoma
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.
