NCI Definition: An aggressive lymphoma that develops in HIV-positive patients. There is a significant increase in the incidence of lymphomas associated with the AIDS epidemic. These lymphomas are usually extranodal, most often express a B-cell phenotype and morphologically are classified as Burkitt, diffuse large B-cell, and Hodgkin lymphomas. The prognosis is closely related to the severity of immunodeficiency. 
There are 2 clinical trials for AIDS-related lymphoma, of which 2 are open and 0 are completed or closed. Of the trials that contain AIDS-related lymphoma as an inclusion criterion, 1 is phase 1 (1 open) and 1 is phase 2 (1 open).
Donor derived hiv-specific t-cells with non-escaped epitope targets, busulfan, and pembrolizumab are the most common interventions in AIDS-related lymphoma clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.