NCI Definition: An invasive carcinoma with glandular differentiation arising from the ampulla of Vater. Signs and symptoms include jaundice, abdominal pain, anorexia, nausea, vomiting, and weight loss. [1]

Disease Details

Adenocarcinoma of Ampulla of Vater, Ampullary Adenocarcinoma, Invasive Adenocarcinoma of the Ampullary Region
Ampulla of Vater Carcinoma
Ampulla of Vater Signet Ring Cell Carcinoma, Ampulla of Vater Clear Cell Adenocarcinoma, Ampulla of Vater Pancreatobiliary Type Adenocarcinoma, Ampulla of Vater Intestinal Type Adenocarcinoma, and Ampulla of Vater Mucinous Adenocarcinoma


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.