Overview

NCI Definition: An oligoastrocytoma characterized by the presence of increased cellularity, nuclear atypia, pleomorphism, and high mitotic activity. [1]

Significant Genes in Anaplastic Oligoastrocytoma

ATRX +

EGFR +

H3F3A +

TP53 +

Disease Details

Synonyms
Anaplastic oligoastrocytoma, WHO grade III, Anaplastic Mixed Glioma, WHO Grade III Mixed Glioma
Parent(s)
WHO Grade III Glioma
OncoTree Name
Anaplastic Oligoastrocytoma
OncoTree Code
AOAST

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.