Overview

Anaplastic oligodendrogliomas most frequently harbor alterations in IDH1, CIC, PIK3CA, NOTCH1, and IDH2 [2].

Most Commonly Altered Genes in Anaplastic Oligodendroglioma

IDH1 Mutation, IDH1 Codon 132 Missense, IDH1 R132H, PIK3CA Mutation (somatic), and PIK3CA Mutation are the most common alterations in anaplastic oligodendroglioma [2].

Top Alterations in Anaplastic Oligodendroglioma

Significant Genes in Anaplastic Oligodendroglioma

EGFR +

FGF1 +

FGF10 +

FGF11 +

FGF12 +

FGF13 +

FGF14 +

FGF16 +

FGF17 +

FGF18 +

FGF19 +

FGF2 +

FGF20 +

FGF21 +

FGF22 +

FGF23 +

FGF3 +

FGF4 +

FGF5 +

FGF6 +

FGF7 +

FGF8 +

FGF9 +

FGFR1 +

FGFR2 +

FGFR3 +

FGFR4 +

Disease Details

Parent(s)
Oligodendroglioma
OncoTree Name
Anaplastic Oligodendroglioma
OncoTree Code
AODG

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 4. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.