Overview

Biliary tract neoplasms most frequently harbor alterations in TP53, KRAS, ARID1A, CDKN2A, and IDH1 [2].

Most Commonly Altered Genes in Biliary Tract Neoplasm

TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, KRAS Mutation, and ARID1A Mutation are the most common alterations in biliary tract neoplasm [2].

Top Alterations in Biliary Tract Neoplasm

Significant Genes in Biliary Tract Neoplasm

ERBB2 +

ERBB3 +

RICTOR +

Disease Details

Parent(s)
Hepatobiliary Neoplasm
Children
Bile Duct Neoplasm and Gallbladder Neoplasm
OncoTree Name
Biliary Tract
OncoTree Code
BILIARY_TRACT

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.