Overview

NCI Definition: A benign or malignant, primary or metastatic neoplasm of the bladder. - 2003 [1]

Bladder neoplasms most frequently harbor alterations in TP53, KDM6A, KMT2D, FGFR3, and ARID1A [2].

Most Commonly Altered Genes in Bladder Neoplasm

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, FGFR3 Mutation, and KMT2D Mutation are the most common alterations in bladder neoplasm [2].

Top Alterations in Bladder Neoplasm

Disease Details

Synonyms
Tumor of Urinary Bladder, Tumor of the Bladder, Bladder Tumor, Neoplasm of the Bladder, Urinary Bladder Neoplasms, Tumor of Bladder, Urinary Bladder Tumor, Urinary Bladder Tumors, Bladder Tumors, Neoplasm of Bladder, Neoplasm of Urinary Bladder, Urinary Bladder Neoplasm, Neoplasm of the Urinary Bladder, Tumor of the Urinary Bladder
Parent(s)
Bladder/Urinary Tract Neoplasm
Children
Bladder Inflammatory Myofibroblastic Tumor, Benign Bladder Neoplasm, Bladder Villous Adenoma, Bladder Neuroendocrine Neoplasm, Malignant Bladder Neoplasm, Bladder Papillary Urothelial Neoplasm, and Bladder Non-Invasive Urothelial Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.