Overview

NCI Definition: A benign or malignant, primary or metastatic neoplasm of the bladder. - 2003 [1]

Bladder neoplasms most frequently harbor alterations in TP53, KDM6A, KMT2D, FGFR3, and ARID1A [2].

Most Commonly Altered Genes in Bladder Neoplasm

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, FGFR3 Mutation, and KMT2D Mutation are the most common alterations in bladder neoplasm [2].

Top Alterations in Bladder Neoplasm

Disease Details

Synonyms
Neoplasm of Bladder, Bladder Tumor, Urinary Bladder Neoplasm, Tumor of Urinary Bladder, Bladder Tumors, Tumor of Bladder, Tumor of the Urinary Bladder, Urinary Bladder Tumor, Urinary Bladder Tumors, Tumor of the Bladder, Neoplasm of Urinary Bladder, Neoplasm of the Urinary Bladder, Neoplasm of the Bladder, Urinary Bladder Neoplasms
Parent(s)
Bladder/Urinary Tract Neoplasm
Children
Benign Bladder Neoplasm, Bladder Villous Adenoma, Malignant Bladder Neoplasm, Bladder Papillary Urothelial Neoplasm, Bladder Soft Tissue Neoplasm, Bladder Non-Invasive Urothelial Neoplasm, and Bladder Neuroendocrine Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.