NCI Definition: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage. 
Bone neoplasms most frequently harbor alterations in TP53, CDKN2A, CDKN2B, IDH1, and RB1 .
TP53 Mutation, CDKN2A Loss, CDKN2B Loss, IDH1 Mutation, and IDH1 Codon 132 Missense are the most common alterations in bone neoplasm .
There is 1 clinical trial for bone neoplasm, of which 0 are open and 1 is completed or closed. Of the trial that contains bone neoplasm as an inclusion criterion, 1 is phase 3 (0 open).
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.