Diseases /
Bone Neoplasm
Overview
NCI Definition: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage. [1]
Bone neoplasms most frequently harbor alterations in TP53, CDKN2A, CDKN2B, IDH1, and RB1 [2].
TP53 Mutation, CDKN2A Loss, CDKN2B Loss, IDH1 Mutation, and IDH1 Codon 132 Missense are the most common alterations in bone neoplasm [2].
Clinical Trials
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.