NCI Definition: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage. 
Bone neoplasms most frequently harbor alterations in TP53, IDH1, CDKN2A, CDKN2B, and RB1 .
TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, IDH1 Mutation, and IDH1 Codon 132 Missense are the most common alterations in bone neoplasm .
There is 1 clinical trial for bone neoplasm, of which 1 is open and 0 are completed or closed. Of the trial that contains bone neoplasm as an inclusion criterion, 1 is phase 3 (1 open).
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.