Diseases /
Brain Neoplasm
Overview
NCI Definition: A benign or malignant neoplasm that arises from or metastasizes to the brain. [1]
Brain neoplasms most frequently harbor alterations in TP53, KMT2D, PIK3CA, H3F3A, and CTNNB1 [2].
TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, KMT2D Mutation, and H3F3A Mutation are the most common alterations in brain neoplasm [2].
Clinical Trials
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.