Overview

Gene Location [1]
Xq12
Pathway
Hormone signaling

Biomarker-Directed Therapies

Significance of AR Positive in Diseases

Breast Carcinoma +

Malignant Salivary Gland Neoplasm +

Prostate Carcinoma +

Adenocarcinoma Of Unknown Primary +

Bladder Carcinoma +

Clear Cell Renal Cell Carcinoma +

Fallopian Tube Carcinoma +

Invasive Breast Carcinoma +

Malignant Solid Tumor +

Ovarian Carcinoma +

Pancreatic Carcinoma +

Primary Peritoneal Carcinoma +

Prostate Adenocarcinoma +

Renal Pelvis And Ureter Carcinoma +

Salivary Duct Carcinoma +

Salivary Gland Carcinoma +

Urethral Carcinoma +

Urothelial Carcinoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. Liu X, Wu C, Li C, and Boerwinkle E. dbNSFP v3.0: A one-stop database of functional predictions and annotations for human nonsynonymous and splice site SNVs. Human Mutation. 2015;37:235-241.

Liu X, Jian X, and Boerwinkle E. dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions. Human Mutation. 2011;32:894-899.

4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

5. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.