Overview

Breast ductal carcinomas most frequently harbor alterations in TP53, PIK3CA, GATA3, ERBB2, and CCND1 [2].

Most Commonly Altered Genes in Breast Ductal Carcinoma

PIK3CA Mutation, TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, and PIK3CA Codon 1047 Missense are the most common alterations in breast ductal carcinoma [2].

Top Alterations in Breast Ductal Carcinoma

Disease Details

Synonyms
Ductal Breast Carcinoma
Parent(s)
Breast Adenocarcinoma
Children
Breast Invasive Ductal Carcinoma, Ductal Carcinoma In Situ, Papillary Breast Carcinoma, and Apocrine Breast Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.