Overview

Breast invasive ductal carcinomas most frequently harbor alterations in TP53, PIK3CA, GATA3, ERBB2, and CCND1 [2].

Most Commonly Altered Genes in Breast Invasive Ductal Carcinoma

PIK3CA Mutation, TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, and PIK3CA Codon 1047 Missense are the most common alterations in breast invasive ductal carcinoma [2].

Top Alterations in Breast Invasive Ductal Carcinoma

Significant Genes in Breast Invasive Ductal Carcinoma

ERBB2 +

Disease Details

Synonyms
Breast invasive ductal carcinoma (IDC)
Parent(s)
Breast Ductal Carcinoma
Children
Mucinous Breast Carcinoma, Secretory Breast Carcinoma, Lipid-Rich Breast Carcinoma, Acinic Cell Breast Carcinoma, Invasive Apocrine Breast Carcinoma, Medullary Breast Carcinoma, Invasive Ductal Carcinoma, Not Otherwise Specified, and Tubular Breast Carcinoma
OncoTree Name
Breast Invasive Ductal Carcinoma
OncoTree Code
IDC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.