Associated Genetic Biomarkers

Overview

NCI Definition: A lung carcinoma arising from the bronchial epithelium. [1]

Significant Genes in Bronchogenic Carcinoma

AKT1 +

ALK +

ATM +

ATR +

BRAF +

BRCA1 +

BRCA2 +

CCND1 +

CDK12 +

CDK4 +

CDK6 +

CDKN2A +

CHEK2 +

CSF1R +

EGFR +

EPCAM +

ERBB2 +

ERBB3 +

EXO1 +

FANCA +

FGFR1 +

FGFR2 +

FGFR3 +

FLT1 +

FLT3 +

FLT4 +

KDR +

KIT +

MET +

MLH1 +

MLH3 +

MRE11A +

MSH2 +

MSH3 +

MSH6 +

MST1R +

MTOR +

NBN +

NRG1 +

NTRK1 +

NTRK2 +

NTRK3 +

PALB2 +

PCNA +

PDGFRA +

PDGFRB +

PIK3CA +

PMS1 +

PMS2 +

POLD1 +

POLE +

RAD51C +

RAF1 +

RET +

RFC1 +

RFC2 +

RFC3 +

RFC4 +

RFC5 +

ROS1 +

RPA1 +

RPA2 +

RPA3 +

RPA4 +

SSBP1 +

TSC1 +

TSC2 +

VHL +

Disease Details

Synonyms
Bronchial Carcinoma, Bronchiogenic Carcinoma, Bronchogenic Lung Carcinoma, CARCINOMA, BRONCHIAL, MALIGNANT
Parent(s)
Lung Carcinoma
Children
Superior Sulcus Lung Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.