Overview

NCI Definition: A molecularly distinct B-cell lymphoma reminiscent of Burkitt lymphoma. It is characterized by the absence of MYC translocation and the presence of chromosome 11q aberrations. [1]

Significant Genes in Burkitt-Like Lymphoma with 11q Aberration

BCL2 +

BCL6 +

MYC +

Disease Details

Synonyms
MYC-Negative High-Grade B-Cell Lymphoma with 11q Aberration Resembling Burkitt Lymphoma, MYC-Negative B-Cell Lymphoma with 11q Aberration Resembling Burkitt Lymphoma, B-Cell Lymphoma with 11q Aberration Resembling Burkitt Lymphoma
Parent(s)
Mature B-Cell Non-Hodgkin Lymphoma
OncoTree Name
Burkitt-Like Lymphoma with 11q Aberration
OncoTree Code
BLL11Q

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.