NCI Definition: A malignant epithelial neoplasm which is confined to the epithelial layer without evidence of further tissue invasion. [1]

Disease Details

CARCINOMA, IN SITU, MALIGNANT, Epithelial Tumor, In situ, Malignant, stage 0 disease, CIS, Intraepithelial Carcinoma, Non-invasive Carcinoma
Pre-malignant Neoplasm
Adenocarcinoma In Situ, Penile Carcinoma In Situ, Stage 0 Laryngeal Cancer, Oral Cavity Carcinoma In Situ, Tracheal Carcinoma In Situ, Stage 0 Nasal Cavity Cancer, Grade III Prostatic Intraepithelial Neoplasia, Stage 0 Skin Cancer, Stage 0 Rectal Cancer, Breast Carcinoma In Situ, Stage 0 Esophageal Cancer AJCC v6, Stage 0 Gastric Cancer, Stage 0 Uterine Corpus Cancer AJCC v6, Stage 0 Colon Cancer, Stage 0is Bladder Urothelial Carcinoma, and Cervical Carcinoma In Situ


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.