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Central Nervous System Germ Cell Tumor

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Overview

NCI Definition: A unique group of rare tumors of the central nervous system that affect mainly children and adolescents. Their morphologic and biologic profile corresponds to that of homologous germ cell tumors that arise in the gonads and in other extragonadal sites. Representative examples include: germinoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma. [1]

Clinical Trials

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Disease Details

Synonyms
Germ Cell Tumor of Central Nervous System, Germ Cell Neoplasm of Central Nervous System, Germ Cell Neoplasm of CNS, Germ Cell Tumor of CNS, Central Nervous System Germ Cell Neoplasm, Germ Cell Neoplasm of the CNS, CNS Germ Cell Tumor, Germ Cell Neoplasm of the Central Nervous System, CNS Germ Cell Neoplasm, Germ Cell Tumor of the CNS, Germ Cell Tumor of the Central Nervous System
Parent(s)
Extragonadal Germ Cell Tumor
Children
Central Nervous System Teratoma, Pineal Region Germ Cell Tumor, Childhood Central Nervous System Germ Cell Tumor, Central Nervous System Childhood Germ Cell Tumor, Malignant Central Nervous System Germ Cell Tumor, Adult Central Nervous System Germ Cell Tumor, and Central Nervous System Adult Germ Cell Tumor
OncoTree Name
Germ Cell Tumor, Brain
OncoTree Code
BGCT

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.