Overview

NCI Definition: A melanoma that affects the central nervous system. It is characterized by pleomorphism, melanin pigmentation, a high mitotic rate, necrosis, and hemorrhage. It is a highly aggressive and radioresistant tumor. The prognosis is usually poor. [1]

Disease Details

Synonyms
Melanoma of Central Nervous System, Melanoma of the Central Nervous System, Melanoma of CNS, Melanoma of the CNS, CNS Melanoma
Parent(s)
Non-Cutaneous Melanoma
Children
Spinal Cord Melanoma and Meningeal Melanoma
OncoTree Name
Primary CNS Melanoma
OncoTree Code
PCNSM

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.