Overview

Cervical neuroendocrine carcinomas most frequently harbor alterations in MYC, TP53, RB1, SF3B1, and RGS13 [2].

Most Commonly Altered Genes in Cervical Neuroendocrine Carcinoma

MYC Amplification, TP53 c.217-c.1178 Missense, TP53 Mutation, TP53 Missense, and TP53 Exon 7 Mutation are the most common alterations in cervical neuroendocrine carcinoma [2].

Top Alterations in Cervical Neuroendocrine Carcinoma

Disease Details

Parent(s)
Neuroendocrine Carcinoma
Children
Cervical Small Cell Carcinoma and Cervical Large Cell Neuroendocrine Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.