Associated Genetic Biomarkers

Overview

NCI Definition: An abnormal growth of the cells that comprise the tissues of the brainstem. While the tumor may be histologically benign, it can produce great morbidity due to its location. It presents most commonly in the first two decades of life. [1]

Significant Genes in Childhood Brain Stem Glioma

RB1 +

Disease Details

Synonyms
Pediatric Glioma of Brainstem, Childhood Brainstem Glioma, Pediatric Glioma of the Brainstem, Pediatric Glioma of Brain Stem, Pediatric Brainstem Glioma, Childhood Glioma of the Brainstem, Childhood Glioma of the Brain Stem, Childhood Glioma of Brain Stem, Childhood Glioma of Brainstem, Pediatric Glioma of the Brain Stem, Pediatric Brain Stem Glioma
Parent(s)
Childhood Brain Stem Neoplasm
Children
Childhood Brain Stem Astrocytoma and Diffuse Intrinsic Pontine Glioma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.