Overview

NCI Definition: A uveal melanoma that arises from the choroid. It is the most common primary malignant intraocular tumor. It usually affects Caucasians of northern European descent. It usually remains asymptomatic for a long period. When signs and symptoms occur, they include blurred vision, visual field loss, floaters, and ocular pain. Tumor size is the most important factor that relates to prognosis. [1]

Disease Details

Synonyms
Melanoma of the Choroid, Choroid Malignant Melanoma, Melanoma of Choroid, Choroidal Melanoma, Malignant Melanoma of Choroid, Malignant Melanoma of the Choroid
Parent(s)
Malignant Choroid Neoplasm
Children
Choroid Mixed Cell Melanoma, Choroid Epithelioid Cell Melanoma, Intermediate Cell Type Choroid Melanoma, Choroid Spindle Cell Melanoma, and Choroid Necrotic Melanoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.