Overview

NCI Definition: An intraventricular papillary neoplasm that originates from the choroid plexus epithelium. It includes the choroid plexus papilloma, atypical choroid plexus papilloma, and choroid plexus carcinoma. [1]

Choroid plexus neoplasms most frequently harbor alterations in TP53 [2].

Most Commonly Altered Genes in Choroid Plexus Neoplasm

TP53 c.217-c.1178 Missense, TP53 Mutation, and TP53 Missense are the most common alterations in choroid plexus neoplasm [2].

Top Alterations in Choroid Plexus Neoplasm

Significant Genes in Choroid Plexus Neoplasm

MYCN +

Disease Details

Synonyms
Neoplasm of Choroid Plexus, Choroid Plexus Tumor, Tumor of Choroid Plexus, Neoplasm of the Choroid Plexus, Tumor of the Choroid Plexus
Parent(s)
Intraventricular Brain Neoplasm
Children
Malignant Choroid Plexus Neoplasm, Childhood Choroid Plexus Neoplasm, Atypical Choroid Plexus Papilloma, Choroid Plexus Papilloma, and Adult Choroid Plexus Neoplasm
OncoTree Name
Choroid Plexus Tumor
OncoTree Code
CPT

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.