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Chromophobe Renal Cell Carcinoma

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Overview

NCI Definition: A type of carcinoma that comprises a minority of renal cell carcinomas. It is characterized by loss of chromosomes 1 and Y. Based on the cytoplasmic characteristics of the neoplastic cells, this type of carcinoma is classified as classic (typical) or eosinophilic. It has a much better prognosis than other renal cell carcinomas. [1]

Clinical Trials

View Clinical Trials for Chromophobe Renal Cell Carcinoma

Significant Genes in Chromophobe Renal Cell Carcinoma

SDHB +

TFE3 +

TSC1 +

Disease Details

Synonyms
Renal Cell Carcinoma, Chromophobe Type, Chromophobe Cell Carcinoma of Kidney, Chromophobe Carcinoma of the Kidney, Chromophobe Carcinoma, Chromophobe Cell Carcinoma of the Kidney, Chromophobe Carcinoma of Kidney, Chromophobe Adenocarcinoma
Parent(s)
Non-Clear Cell Renal Cell Carcinoma
Children
Classic Variant of Chromophobe Renal Cell Carcinoma and Eosinophilic Variant of Chromophobe Renal Cell Carcinoma
OncoTree Name
Chromophobe Renal Cell Carcinoma
OncoTree Code
CHRCC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.