Overview

NCI Definition: A chronic myelomonocytic leukemia characterized by the presence of 10-19 percent blasts in the bone marrow and 5-19 percent blasts in the peripheral blood or by the presence of Auer rods regardless of the blasts count. [1]

Significant Genes in Chronic Myelomonocytic Leukemia-2

ASXL1 +

MECOM +

MLF1 +

NPM1 +

NRAS +

RPN1 +

RUNX1 +

SETBP1 +

TP53 +

Disease Details

Synonyms
CMML-2
Parent(s)
Chronic Myelomonocytic Leukemia
OncoTree Name
Chronic Myelomonocytic Leukemia-2
OncoTree Code
CMML2

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.