Diseases /
Clear Cell Adenocarcinoma
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Associated Genetic Biomarkers
Overview
NCI Definition: A malignant neoplasm composed of glandular epithelial clear cells. Various architectural patterns may be seen, including papillary, tubulocystic, and solid. [1]
Clear cell adenocarcinomas most frequently harbor alterations in VHL, PBRM1, SETD2, BAP1, and TP53 [2].
VHL Mutation, PBRM1fs, PBRM1 Mutation, SETD2 Mutation, and TP53 Mutation are the most common alterations in clear cell adenocarcinoma [2].
Clinical Trials
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.