Overview

NCI Definition: A malignant neoplasm composed of glandular epithelial clear cells. Various architectural patterns may be seen, including papillary, tubulocystic, and solid. [1]

Significant Genes in Clear Cell Adenocarcinoma

MLH1 +

MLH3 +

MSH2 +

MSH3 +

MSH6 +

PMS1 +

PMS2 +

Disease Details

Synonyms
Mesonephroid Clear Cell Adenocarcinoma, Mesonephroid Clear Cell Carcinoma, ADENOCARCINOMA, CLEAR CELL, MALIGNANT, Clear Cell Carcinoma
Parent(s)
Adenocarcinoma
Children
Endometrial Clear Cell Adenocarcinoma, Hidradenocarcinoma, Urethral Clear Cell Adenocarcinoma, Extrahepatic Bile Duct Clear Cell Adenocarcinoma, Cervical Clear Cell Adenocarcinoma, Bladder Clear Cell Adenocarcinoma, Ovarian Clear Cell Adenocarcinoma, Fallopian Tube Clear Cell Adenocarcinoma, Uterine Ligament Clear Cell Adenocarcinoma, Ampulla of Vater Clear Cell Adenocarcinoma, Primary Peritoneal Clear Cell Carcinoma, and Clear Cell Renal Cell Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.