Overview

NCI Definition: A rare malignant neoplasm with melanocytic differentiation characterized by the presence of polygonal or spindle shaped clear cells. This sarcoma usually affects the tendons and aponeuroses and is associated with a poor prognosis due to recurrences and metastases. [1]

Significant Genes in Clear Cell Sarcoma of Soft Tissue

ATF1 +

AXL +

EWSR1 +

MET +

RET +

Disease Details

Synonyms
Chordoid Sarcoma, Malignant Melanoma of the Soft Parts, Malignant Melanoma of Soft Parts, Soft tissue clear cell sarcoma, Clear cell sarcoma - not kidney, Clear cell sarcoma/Malignant melanoma of soft parts (excluding Clear cell sarcoma of the kidney), Clear Cell Sarcoma of Soft Parts
Parent(s)
Soft Tissue Sarcoma
OncoTree Name
Clear Cell Sarcoma
OncoTree Code
CCS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.