NCI Definition: Also known as collecting duct carcinoma, this is a rare type of renal carcinoma. It arises from the collecting ducts of the renal medulla, and most authors suggest that this is an aggressive tumor. [1]

Collecting duct carcinomas most frequently harbor alterations in NF2, CDKN2A, FBXW7, CDKN2B, and SMARCB1 [2].

Most Commonly Altered Genes in Collecting Duct Carcinoma

NF2fs, FBXW7 Mutation, CDKN2B Loss, CDKN2A Loss, and SETD2 Mutation are the most common alterations in collecting duct carcinoma [2].

Top Alterations in Collecting Duct Carcinoma

Disease Details

Carcinoma of the Kidney Collecting Duct, Bellini Duct Carcinoma, Carcinoma of Collecting Ducts of Bellini, Carcinoma of Kidney Collecting Duct, Carcinoma of the Collecting Ducts of Bellini, Collecting duct renal cancer, Carcinoma of the Renal Collecting Duct, Renal Collecting Duct Carcinoma, Collecting Duct Renal Cell Carcinoma, Kidney Collecting Duct Carcinoma, Carcinoma of Renal Collecting Duct, BDC
Non-Clear Cell Renal Cell Carcinoma
OncoTree Name
Collecting Duct Renal Cell Carcinoma
OncoTree Code


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.