Overview

Colorectal neuroendocrine neoplasms most frequently harbor alterations in TP53, APC, KRAS, BRAF, and RB1 [2].

Most Commonly Altered Genes in Colorectal Neuroendocrine Neoplasm

TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, APC Mutation, and KRAS Mutation are the most common alterations in colorectal neuroendocrine neoplasm [2].

Top Alterations in Colorectal Neuroendocrine Neoplasm

Disease Details

Parent(s)
Digestive System Neuroendocrine Neoplasm
Children
Colorectal Neuroendocrine Carcinoma, Rectal Neuroendocrine Neoplasm, Colorectal Neuroendocrine Tumor, and Colon Neuroendocrine Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.