Colorectal Neuroendocrine Neoplasm
Associated Genetic Biomarkers
Colorectal neuroendocrine neoplasms most frequently harbor alterations in TP53, APC, KRAS, BRAF, and RB1 .
TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, APC Mutation, and KRAS Mutation are the most common alterations in colorectal neuroendocrine neoplasm .
There is 1 clinical trial for colorectal neuroendocrine neoplasm, of which 1 is open and 0 are completed or closed. Of the trial that contains colorectal neuroendocrine neoplasm as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
177lu-opsc001 is the most common intervention in colorectal neuroendocrine neoplasm clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.