Overview

Conventional glioblastoma multiformes most frequently harbor alterations in CDKN2A, CDKN2B, PTEN, EGFR, and TP53 [2].

Most Commonly Altered Genes in Conventional Glioblastoma Multiforme

CDKN2A Loss, CDKN2B Loss, TP53 Mutation, PTEN Mutation, and EGFR Amplification are the most common alterations in conventional glioblastoma multiforme [2].

Top Alterations in Conventional Glioblastoma Multiforme

Disease Details

Parent(s)
Glioblastoma
OncoTree Name
Glioblastoma Multiforme
OncoTree Code
GBM

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.