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Conventional Glioblastoma Multiforme

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Overview

Conventional glioblastoma multiformes most frequently harbor alterations in CDKN2A, PTEN, CDKN2B, TP53, and EGFR [2].

Most Commonly Altered Genes in Conventional Glioblastoma Multiforme

CDKN2A Loss, CDKN2B Loss, TP53 Mutation, PTEN Mutation, and TP53 Missense are the most common alterations in conventional glioblastoma multiforme [2].

Top Alterations in Conventional Glioblastoma Multiforme

Clinical Trials

View Clinical Trials for Conventional Glioblastoma Multiforme

Disease Details

Parent(s)
Glioblastoma
OncoTree Name
Glioblastoma Multiforme
OncoTree Code
GBM

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.