Conventional glioblastoma multiformes most frequently harbor alterations in CDKN2A, PTEN, CDKN2B, TP53, and EGFR [2].

Most Commonly Altered Genes in Conventional Glioblastoma Multiforme

CDKN2A Loss, CDKN2B Loss, TP53 Mutation, PTEN Mutation, and TP53 Missense are the most common alterations in conventional glioblastoma multiforme [2].

Top Alterations in Conventional Glioblastoma Multiforme

Disease Details

OncoTree Name
Glioblastoma Multiforme
OncoTree Code


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.