Overview

NCI Definition: A malignant neoplasm that arises from the epithelium of any part of the digestive system. Representative examples include colorectal carcinoma, esophageal carcinoma, and pancreatic carcinoma. [1]

Significant Genes in Digestive System Carcinoma

ERBB2 +

UGT1A1 +

Disease Details

Parent(s)
Malignant Digestive System Neoplasm
Children
Colorectal Carcinoma, Esophagogastric Carcinoma, Anal Carcinoma, Liver and Intrahepatic Bile Duct Carcinoma, Appendix Carcinoma, Pancreatobiliary Carcinoma, and Small Intestinal Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.