Overview

NCI Definition: A rare Epstein-Barr virus-positive B-cell lymphoproliferative disorder which presents as an ulcerative mucocutaneous lesion. It is associated with immune suppression, including age-related and drug-induced immunosuppression. [1]

Significant Genes in EBV-Positive Mucocutaneous Ulcer

AFF1 +

ALK +

BCL2 +

BCL6 +

ELL +

IRF4 +

KMT2A +

MLLT1 +

MLLT10 +

MLLT3 +

MLLT4 +

MYC +

NRIP3 +

Disease Details

Synonyms
Epstein Barr virus positive mucocutaneous ulcer, EBV Positive Mucocutaneous Ulcer, EBVMCU, Epstein-Barr Virus-Positive Mucocutaneous Ulcer
Parent(s)
Atypical Lymphoproliferative Disorder
OncoTree Name
EBV Positive Mucocutaneous Ulcer
OncoTree Code
EBVMCU

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.