Overview

NCI Definition: A rare Epstein-Barr virus-positive B-cell lymphoproliferative disorder which presents as an ulcerative mucocutaneous lesion. It is associated with immune suppression, including age-related and drug-induced immunosuppression. [1]

Significant Genes in EBV-Positive Mucocutaneous Ulcer

AFF1 +

ALK +

BCL2 +

BCL6 +

ELL +

IRF4 +

KMT2A +

MLLT1 +

MLLT10 +

MLLT3 +

MLLT4 +

MYC +

Disease Details

Synonyms
Epstein-Barr Virus-Positive Mucocutaneous Ulcer, Epstein Barr virus positive mucocutaneous ulcer, EBVMCU, EBV Positive Mucocutaneous Ulcer
Parent(s)
Atypical Lymphoproliferative Disorder
OncoTree Name
EBV Positive Mucocutaneous Ulcer
OncoTree Code
EBVMCU

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.